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Abstract Background Obesity is a major public health issue. This review updates the evidence on the effectiveness of behavioural and pharmacologic treatments for overweight and obesity in adults.We recommend moving this block and the precedingand injecting drug.
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For a small number of studies, there were no immediate postassessment data; we chose the data point closest to the end of the intervention.
For another small group of on-going studies, we extracted interim data at 12 mo. We extracted data for all reported adverse events. At all levels, inter-rater disagreements were resolved through discussion.
The DerSimonian and Laird random-effects model with an inverse variance method was used to generate the summary measures of effect in the form of mean difference for continuous outcomes and risk ratio RR for binary outcomes.
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