Active substances: Norfloxacin
Norfloxacin Side Effects, Dosage, Interactions... Norfloxacin is an antibiotic in a group of drugs called fluoroquinolones flor o KWIN o lones.
Norfloxacin fights bacteria in the body. Norflox TZ Uses, Side effects and Dosage Glowpink Useful information on Norflox TZ, including it s uses, side effects, dosage information, generic name and precautions that needs to be taken.
Use norfloxacin as ordered by your doctor. Read all information given to you. Follow all instructions closely.
Take norfloxacin at the same time of day.
Pregnancy Norfloxacin has been reported to rapidly cross the blood-placenta and blood-milk barrier, and is extensively distributed into the fetal tissues. For this reason norfloxacin and other fluoroquinolones are contraindicated during pregnancy due to the risk of spontaneous abortions and birth defects.Similarly, DNA damage was noted in the regenerating liver and the livers. Mechanistic study on flumequine hepatocarcinogenicity focusing on DNA damage in mice.
The manufacturer only recommends use of norfloxacin during pregnancy when benefit outweighs risk. Ciprofloxacin is being licensed for the treatment of Complicated Urinary Tract Infections and Pyelonephritis due to Escherichia coli and Inhalational Anthrax post-exposure and levofloxacin was recently licensed for the treatment of Inhalational Anthrax post-exposure.
However, the Fluoroquinolones are licensed to treat lower respiratory infections in children with cystic fibrosis in the UK.
Adverse effects In general, fluoroquinolones are well tolerated, with most side-effects being mild to moderate.
The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients treated with other antibiotic classes. Centers for Disease Control study found patients treated with fluoroquinolones experienced adverse events severe enough to lead to an emergency department visit more frequently than those treated with cephalosporins or macrolides, but less frequently than those treated with penicillins, clindamycin, sulfonamides, or vancomycin.
Among these, tendon problems and exacerbation of the symptoms of the neurological disorder myasthenia gravis are the subject of "black box" warnings in the United States.
Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients. Simultaneous use of corticosteroids is present in almost one-third of quinolone-associated tendon rupture.
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