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Any HIV-uninfected participants who subsequently seroconvert will be managed clinically by the study site according to local practice appropriate counseling, clinical evaluation and immediate linkage to clinical and psychosocial services.
These participants will also be retained in the study unless they choose to discontinue study participation. It is also used to prevent malaria. Doxycycline can also be used in people who cannot be treated with penicillin to treat certain types of food poisoning.
Doxycycline Oracea is used only to treat pimples and bumps caused by rosaceae a skin disease that causes redness, flushing, and pimples on the face.
Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria.
Epidemiologic investigation and case-control analysis. All patients were examined by clinicians for diagnosis, treatment, and counseling.
All case patient and control patient medical records and staff interview forms were reviewed, and follow-up interviews were conducted when necessary for disease control.
The public-health records of all identified sex partners were reviewed for clinical diagnosis, treatment, follow-up, and identification of any additional sex partners.
This process was continued for each related sexual contact until no additional contacts could be identified. As with all syphilis cases in San Francisco, a minimum of 3 attempts were made to contact patients and partners for clinical follow-up, and resolution of symptoms and serologic improvement was confirmed for all contactable persons.
Data from all sources were combined to maximize the available information for performing a retrospective unmatched case-control analysis to identify common demographic or behavioral characteristics or meeting venues that might define a sexual network.
Statistical analyses were performed using Epi Info, version 6.
Of these 533 persons, 154 28. Of these 118 samples, 46 contained mutant 23 S rRNA genes from the group of confirmed case patient, and 72 had wild-type 23 S rRNA genes from the group of control patients.
Six suspect or probable case patients 2, 5, 37, and 45 were identified solely through clinical treatment failure, because no isolates were available for molecular analysis table 1, but they were not included in the case-control analysis table 2.
One case patient 4 was initially identified as a probable case patient after not responding to treatment, but he was subsequently confirmed by the molecular assay 9 table 1.