Active substances: Doxycycline
Accompanying symptoms often include fever, fatigue, chills, and myalgia 5. The clinical presentation of the disease is usually not distinctive, due to the diversity of symptoms, different routes of infection and the infecting dose.
The course of the disease also depends on host factors e. Therefore anamnesis, epidemiological factors and serological tests are important.
Being exposed to livestock, living in rural area or living closely to farms are risk factors. Above that, the lack of direct contact with animals cannot exclude the diagnosis of Q fever, since airborne transmission of C.
In our report, the patient stated a close contact with tropical ruminants. The patient was diagnosed inadvertently, because he was included in the study while asymptomatic; in this sense, approximately half of the infected persons show a wide variety of non-specific clinical signs and symptoms, especially in the tropics, where fevers are common.
Serological tests are based on detecting antibodies against phase I and II of Coxiella. The IFA is the gold standard because it is highly sensitive and specific.
In acute infection, typically the phase II antibodies increase first, whereas in chronic diseases phase I antibodies increase.
Seroconversion usually occurs 7-15 days post-infection. In our case the results can be interpreted as an acute or past infection with C.
In Latin American countries, Q fever is a neglected disease due to high diversity of symptoms, lack of knowledge of the disease and epidemiological data, which most likely lead to underdiagnosis and underreporting of the disease.
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