Active substances: Clomiphene
This action stimulates the growth of the ovarian follicle and thus initiates ovulation. During a normal menstrual cycle only one egg is ovulated.
The use of clomiphene often causes the ovaries to produce two or three eggs per cycle.
Clomiphene is taken orally for 5 days and is active only during the month it is taken. Two to three days after Provera is completed, a menstrual period should begin.
On the 3 rd, 4 th or 5 th day of menstrual flow, a course of clomiphene is started.
A clomiphene citrate 50 mg tablet is taken orally for 5 days. On day 11 or 12 of the menstrual cycle, ultrasound monitoring is conducted to determine if an ovarian follicle or follicles have developed.
Also at this time, patients are asked to use an ovulation predictor kit to test their urine for a surge in LH luteinizing hormone indicating that eggs have matured and ovulation is imminent. Natural intercourse or insemination is timed to ovulation.
If ovulation has been assisted by an hCG injection, a form of the hormone progesterone is given via vaginal tablets or gel.
The progesterone hormone serves to support the endometrial uterine lining and prepare it for the fertilized egg.
If the test is positive, a blood test will be performed to confirm results.
If ovulation doesn't occur during this initial clomiphene dosage, another course of provera will be prescribed and the dose of clomiphene increased until ovulation occurs. This is sometimes referred to as "superovulation.