Active substances: Clomiphene
Clomiphene is a synthetic chemical, taken orally, that binds to estrogen receptors in the brain and causes pituitary FSH levels to rise see below. Gonadotropins are identical to human protein hormones FSH and LH and, given by injection, bypass the pituitary gland and directly stimulate the ovaries.
Clomiphene Citrate treatment Clomiphene is a long trusted oral medication relied upon for its safety, effectiveness and relatively low cost.
Clomiphene is used to treat absent or irregular menstrual cycles ovulation induction, to address a condition called luteal phase defect by increasing progesterone secretion during the second half of the cycle and to make menstrual cycle lengths more predictable, thus improving the timing of intercourse or artificial insemination.
How does Clomiphene Citrate work? Clomiphene triggers the brain's pituitary gland to secrete an increased amount of follicle stimulating hormone FSH and LH luteinizing hormone.
This action stimulates the growth of the ovarian follicle and thus initiates ovulation. During a normal menstrual cycle only one egg is ovulated. The use of clomiphene often causes the ovaries to produce two or three eggs per cycle.
Clomiphene is taken orally for 5 days and is active only during the month it is taken. Two to three days after Provera is completed, a menstrual period should begin.
On the 3 rd, 4 th or 5 th day of menstrual flow, a course of clomiphene is started. A clomiphene citrate 50 mg tablet is taken orally for 5 days.
On day 11 or 12 of the menstrual cycle, ultrasound monitoring is conducted to determine if an ovarian follicle or follicles have developed. Also at this time, patients are asked to use an ovulation predictor kit to test their urine for a surge in LH luteinizing hormone indicating that eggs have matured and ovulation is imminent.
If his level of testosterone is too high, he can take half of a pill every other day. It takes 90 to 108 days from the time that sperm is produced in the testicles until it is ejaculated, so it takes time for a man to see results from Clomid.
As such, a man should not stop taking the medication unless there is no improvement by the fourth month of treatment. If you would like to learn more about fertility options for men at Texas Fertility Center, please contact us today to schedule an appointment.
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No serious adverse events were recorded. A lower level of total cholesterol was verified after three months of treatment. This medication should be considered as a therapeutic option for some patients with symptomatic male testosterone deficiency.