Active substances: Amoxicillin
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In addition levofloxacin presents a good safety profile and is reported to reduce number of side effects. This study was conducted to determine the efficiency of clarithromycin based standard triple therapy on our local population.
Study was also conducted to find out the efficacy of levofloxacin based first line therapy and to compare it with standard triple therapy in terms of efficacy and adverse events. The study was conducted after taking ethical approval from institutional review board.
Purposive sampling technique was used and total 300 newly diagnosed H.
The patients were assured that their information and identity will be kept secret and will not be disclosed and information provided by them will only be used for research purpose.
The relevant information including demographic data, lab investigation results, medicine prescribed and adverse effects were documented on a predesigned proforma.
Patients aging between 18-60 years, fit for gastroscopy procedure were included in this study.
Subjects with active ischaemic heart disease, renal failure, congestive heart failure, history of psychiatric illness or history of use of tranquilizers were excluded from this study.
Patients using non-steroidal anti-inflammatory drugs and those refused to go for gastroscopy procedure were also excluded from study. The baseline blood samples and stool samples of selected patients were collected following standard operating procedures.
Complete blood count.