Active substances: Isotretinoin
Sardana K, Garg V.
Efficacy of low-dose isotretinoin in acne vulgaris. Indian J Dermatol Vernereol Leprol. Isotretinoin Pills — Isotretinoin Simonart T. Newer approaches to the treatment of acne accutane.
Am J Clin Dermatol. Oakley A.
Ministry of Health. Pharmaceutical Claims Isotretinoin.
Comments There are currently no comments for this article. Make a comment. Marked clinical improvement in inflammation, flattening of papulopustular lesions, started 1 or 2 months after initiation of treatment.
Pustules tend to clear more rapidly than papules or nodules, and the lesions on the face, and upper arms, responded more quickly than trunk lesions. There are different opinions about the dose of isotretinoin for treatment of acne.
The suggested standard dose is 0. Low dose isotretinoin to treat acne, has been tried previously. The higher values 96. Hermes et al.
None stopped treatment. Relapse is reported more frequently following treatment with a lower dose. Relapse occurred in 16. Relapses were more common in females with polycystic ovarian disease. These relapses controlled with topical therapy alone or combined with oral antibiotics.
The relapse rate observed by us was lower than that of above mentioned studies. Table 3 Open in a separate window In a study by Amichai et al. Patients at increased risk for early relapse included younger patients with acne of relatively recent onset, those with truncal acne, and women with polycystic ovary syndrome.
Sebaceous hyperplasia: sys- temic treatment with isotretinoin.